Tricarboxylic acids and derivatives
Accela Chembio Inc Triethyl Methanetricarboxylate | 25g | 6279-86-3 | MFCD00009150 | 95+% | D: 1.095 | Shelf Life: 1080 Days | Regular
Triethyl Methanetricarboxylate | 25g | 6279-86-3 | MFCD00009150 | 95+% | D: 1.095 | Shelf Life: 1080 Days | Regular
TARGETMOL CHEMICALS INC Zoledronic acid monohydrate
Also available in 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity. Purity ≥95%
Medchemexpress LLC Pacritinib (citrate) | 1228923-42-9 | 99.7% | 664.70 | 1 ML
Pacritinib (SB1518) citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). This compound can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
- Potent inhibitor of wild-type JAK2 (IC50=23 nM)
- Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
- Inhibits FLT3 (IC50=22 nM)
- Inhibits FLT3D835Y mutant (IC50=6 nM)
- Used for research in acute myeloid leukemia (AML) and myelofibrosis (MF)
Aat Bioquest Dihydrofluorescein diacetate [Fluorescin diacetate] *CAS 35340-49-9*
Dihydrofluorescein diacetate (also called fluorescin diacetate) is hydrolyzed by cellular esterases to dihydrofluorescein (also called fluorescin) and is then oxidized to fluorescein primarily by H2O2.
Alkali Scientific L (+) Rhamnose, Monohydrate, 500 G
L (+) Rhamnose Monohydrate is a high-purity sugar used in laboratory applications, especially in studies of bacterial metabolism and plant biology. This 500-gram supply is ideal for experiments requiring a consistent and reliable source of rhamnose. It is commonly used in biochemical assays, microbiological testing, and as a substrate in fermentation processes. The monohydrate form ensures accurate and reproducible results in laboratory experiments. Rhamnose is used in research on plant cell wall metabolism, microbial growth studies, and other applications where precise sugar control is critical. This bulk quantity is perfect for continuous research and experimental work.
Medchemexpress LLC Ferric citrate | 3522-50-7 | 244.94 | 100 MG
Ferric citrate (Iron(III) citrate) is an orally active iron supplement and an efficacious phosphate binder. It is used for research related to iron deficiency anemia and chronic kidney disease (CKD).
- Orally active iron supplement.
- Efficacious phosphate binder.
- Can be used for iron deficiency anemia and chronic kidney disease (CKD) research.
- Reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease.
- Increases iron stores and reduces intravenous iron and erythropoietin-stimulating agent use while maintaining hemoglobin.
- Can increase transferrin saturation, serum ferritin, and hemoglobin.
Sigma Aldrich Fine Chemicals Biosciences Sodium Citrate Tribasic Dihydrate | 6132-04-3 | MFCD00150031 | 100g
Sodium Citrate Tribasic Dihydrate | Purity: 99% | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 100g
Teknova 20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate dihydrate, 6132-04-3, MFCD00150031, 1 kg
Linear Formula: HOC(COONa)(CH2COONa)2 · 2H2O, Molecular Weight: 294.10, ≥99%, FG, Synonym: Citric acid trisodium salt dihydrate, Sodium citrate tribasic dihydrate, Trisodium citrate dihydrate. Sodium citrate dihydrate is used as a buffer, pH controlling agent, emulsifier, sequestrant and complexing agent in food industry.
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC SPD-473 citrate | 161190-26-7 | MFCD31382144 | 99.8% | 552.47 g/mol | C23H31Cl2NO8S | 1 MG
SPD-473 citrate is the citrate salt of a triple reuptake inhibitor that blocks serotonin, dopamine, and norepinephrine transporters. Supplied for research use, it is a characterized white to off-white solid with documented purity and solubility data for in vitro and in vivo studies.
- Acts as a serotonin, dopamine, and norepinephrine reuptake inhibitor.
- High purity (99.8%).
- Molecular weight 552.47 g/mol.
- White to off-white solid suitable for laboratory handling.
- High solubility in DMSO (100 mg/mL); in vivo formulation protocols provided.
- Available in 1 mg, 5 mg, 10 mg, and 25 mg pack sizes for screening and pilot studies.
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate tribasic dihydrate BioUltra, for molecular biology | 6132-04-3 | MFCD00150031 | 250g
Sodium citrate tribasic dihydrate BioUltra, for molecular biology | 99.5% | MW: 294.1 | 6132-04-3 | MFCD00150031 | 250g
Medchemexpress LLC 3-Thiophenecarboxylic acid, 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methyl-, methyl ester | 544450-68-2 | 99.94% | 337.82 | 100 MG
COR659 is a potent and effective GABAB positive allosteric modulator (PAM) that suppresses alcohol and chocolate self-administration in rats. Its effects are exerted through a composite mechanism, involving positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor.
- Potent and effective GABAB positive allosteric modulator (PAM).
- Suppresses alcohol and chocolate self-administration in rats.
- Exerts effects through a composite mechanism.
- Involves positive allosteric modulation of the GABAB receptor.
- Acts at the cannabinoid CB1 receptor.
- Has shown cytotoxicity against mouse NIH/3T3 cells with an IC50 of 59 μM.
- Relevant to research in neurological, eye or ear disease, neurodegenerative disease, depression, Alzheimer's disease, and Parkinson's disease.
Medchemexpress LLC Azido-PEG2-CH2COOH | 882518-90-3 | 99.0% | 189.17 | 250 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions when combined with molecules containing DBCO or BCN groups.
- PROTAC linker for PROTAC synthesis
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups